After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body, Maged Younes, chair of the European Food Safety Authority's expert Panel on Food Additives and Flavourings, said in a May 2021 statement.

The disadvantage of Titanium Dioxide is that it's not cosmetically elegant, meaning it's a white, unspreadable mess. Sunscreens containing Titanium Dioxide are often hard to spread on the skin and they leave a disturbing whitish tint. The cosmetic industry is, of course, really trying to solve this problem and the best solution so far is using nanoparticles. The itsy-bitsy Nano-sized particles improve both spreadability and reduce the whitish tint a lot, but unfortunately, it also introduces new health concerns. 

China’s government is working on its plan to eliminate outmoded capacities of TiO2 and strengthen environmental protection measurements. Small and middle-sized enterprises, with a production capacity under 50,000t/a, are the ones to suffer. They mostly get merged or need to withdraw from the market. Without their production capacity of about 500,000 tonnes yearly, the domestic output might shrink about 20%. This will enhance the power of listed companies in China immensely, which is one of the main reasons for the effort to go public.